What is ngTMA® ?
ngTMA® is our way of constructing tissue microarrays. As strong believers in a personalized medicine approach, tissue biomarkers and digitization in pathology, we make these tissue microarrays by integrating exceptional technology and our more-than-a-decade long experience in designing tissue microarrays, investigating and validating biomarkers. Without a doubt, the value and reproducibility of tissue biomarkers and their results can be improved using ngTMA®. Moreover, ngTMA® supports molecular studies (e.g. RNA seq) through precise punching of tissue cores, and when combined with clinical data can be of enormous value for establishing artificial intelligence algorithms.
“Our collaborations with the ngTMA team, involving their truly “next generation” human tissue microarrays, have been crucial to support the postulated existence in human cancers of new mechanisms of tumor progression identified in preclinical models, resulting in high profile co-authored publications in Cancer Cell (2018) and Nature (2019), with more exciting stories in the pipeline.”
— Prof. Douglas Hanahan, Director of Swiss Institute for Experimental Cancer Research (EPFL, Switzerland)
What makes ngTMA® unique?
ngTMA® is based on a novel workflow including scientific consulting + TMA design, digital slide annotation, automated tissue punching and documentation for quality control. Our platform is embedded in an innovative research framework and as part of the Translational Research Unit (TRU), Institute of Pathology, University of Bern, has expertise in tissue-related technology. Through partnerships with our pathologists, Tissue Bank Bern (TBB) and Insel Data Science Center, we have access to high-quality tissue samples with documented pre-analytics and detailed patient-related data.
“ngTMA has been a key part of our research projects by meticulously assembling the high quality tissue micro arrays we need for multiparameter imaging techniques. Their work is superb and their staff is a pleasure to work with”
— DR McIlwain and C Schürch - Garry Nolan Lab (University of Stanford, US)
What does ngTMA® include?
Consultation and project design
Freshly cut H&E slides and digital scans
Access to our online image management system (CC)
Training in digital TMA annotation
Your ngTMA® blocks, H&E and TMA grid
Detailed documentation of your TMA
Access to additional services and image analysis tools
“ngTMA solves your «tissue related unknowns»”
— Prof. Aurel Perren - Director of the Institute of Pathology (University of Bern, Switzerland)
“I very much enjoy the high technical standards of ngTMA and their professional advice”
— Prof. Sven Rottenberg - Director of the Institute of Animal Pathology (University of Bern, Switzerland)
ngTMA® meets high-quality standards
Our ngTMA® blocks are part of Tissue Bank Bern (TBB), certified with Vita, Norma and Optima labels from the Swiss Biobanking Platform (SBP). Our TBB staff is trained in Good Clinical Practice and work according to the HFG 2014 (Swiss Law for Research Involving Human Beings).
“Prof. Zlobec’s team developed their own market-leading ngTMA solution and services that we are very proud of. We are looking forward to a continued partnership!”
— Dr. Béla Molnár, CEO 3DHISTECH (Budapest, Hungary)
We thank our collaborators
